Scientist/Senior Scientist – Protein Production

Protein Production · Oxford, Oxfordshire
Department Protein Production
Employment Type Full-Time
Minimum Experience Experienced
Compensation Competetive


July/August 2021

Scientist/Senior Scientist – Protein Production

SpyBiotech is a life sciences biotech company, we are backed by highly respected venture capital investors and are transforming the global vaccine landscape through our ground-breaking protein superglue technology.

Our unique technology platform has opened-up the possibility of delivering life-saving vaccines against major health challenges.  We are rapidly expanding and we are seeking an additional highly motivated scientist to be part of our exciting high growth, high potential journey.


As a scientist, you are expected to actively participate in our preclinical research program developing novel vaccine candidates.  Based at the company’s state-of-the-art laboratories in Oxford Business Park, South Oxford, you will be joined by a team of enthusiastic and like-minded scientists who thrive on research innovation and excellence.


The Opportunity

Using our core technology, the SpyTag/SpyCatcher protein superglue, you will be part of the preclinical vaccine development team working on the production of vaccine candidates against infectious diseases.  The position involves supporting the on-going programme of vaccine development with a particular emphasis on recombinant protein production, purification, and QC analysis. Further, you will provide scientific and technical support where required to advance activities pertaining to research and development and quality control. 


We are seeking a highly organised and motivated individual, with previous experience in protein expression, purification, and analysis. You will have good interpersonal skills and be able to interact productively and accurately with other team members. Previous laboratory experience, good teamwork, and the ability to innovate are essential.

There is significant excitement about the technology in the field, thus this position offers excellent career progression as the company grows from strength to strength.

Key responsibilities

  • Investigate new methodologies that can be applied to the production, purification, and QC of new proteins.
  • Attend training in technical areas as required by the research projects.
  • Produce well-written, compliant, and traceable laboratory notebooks and raw data files.
  • Write and review protocols and SOPs when required.
  • Contribute to the efficient running, cleanliness, and tidiness of the laboratory.


Selection criteria


  • A degree in a relevant biological subject.
  • Experience in recombinant protein expression, particularly baculovirus-insect cell systems.
  • Experience in operating AKTA FPLC systems.
  • Experience in protein analysis.
  • Self-motivated, technically competent, and capable of working independently in a laboratory.
  • Keen to learn new techniques.
  • Excellent organisational and interpersonal skills.
  • Ability to adapt to changing demands whilst operating under pressure to deadlines.
  • Good documentation and computer proficiency (Excel, PowerPoint, and Word).
  • High-level of attention to detail.
  • Ability to write factual reports.



  • Sterile technique and experience in tissue culture.
  • Experience in working with specific virus-like-particles (VLP), especially HBsAg.





  • Competitive Salary
  • Discretionary Bonus (subject to performance)
  • Flexible working hours and the ability to work from home as necessary.
  • 30 days’ holiday per year plus bank holidays


  • Pension: We automatically enrol you in a generous pension scheme with Royal London and will match your contributions up to 10% of salary


  • Community: complimentary breakfast/fresh fruit in the office regular team lunches/pizza; company bi-annual social events (Summer and Christmas)


  • Health & wellbeing: Private Medical Insurance; Excellent Personal Life Insurance; Employee Assistance programme 24/7 discounted subscriptions to various mental and physical health products and services including a gift box on your birthday


  • Family: Paid maternity, paternity, adoption, or shared parental leave, if you have been with us for at least 26 weeks


  • Personal development: Learning budget for books, training courses and conferences


  • Commuting: Member of cycle-to-work scheme





Thank You

Your application was submitted successfully.

  • Location
    Oxford, Oxfordshire
  • Department
    Protein Production
  • Employment Type
  • Minimum Experience
  • Compensation